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For decades, a fundamental question about the difficulty of computing in high-dimensional spaces has resisted proof. New research resolves this question, removing a major theoretical obstacle to understanding the efficiency of randomized algorithms used across science and computing. The Kannan–Lovász–Simonovits (KLS) conjecture was proposed in 1995. It asks whether, for a broad class of high-dimensional…

Lab Director Chris White has worked on research challenges with real-world implications—from new approaches to wartime data analysis to tools for combating human trafficking. He talks to program manager Weishung Liu about the influences that led to the work and more.
Zero-knowledge proofs can verify computing results without rerunning workloads or exposing sensitive data. Magnetar helps bring them into the mainstream with support for standard programming languages, major speed gains, and quantum-resistant security.

StudentSim is a research system for evaluating and improving AI tutoring tools before they are tested with learners. It models how individuals may engage with tutors, giving feedback to improve tutor performance across subjects like chess, writing, and mathematics.

Training AI agents with reinforcement learning can be challenging because their tools, context, and decision-making are managed by complex frameworks. Agent Lightning connects existing agents to RL training, making it easier to improve them without rebuilding them.

Jennifer Neville did not want to go into computer science—but that’s exactly where she landed. Neville discusses the starts and stops that led to her professional sweet spot and her work identifying “surprising failures” making it hard for AI to handle complexity.
Biology doesn't operate in silos, and neither should the AI representation of it. Quine is an early-stage research effort to create a multimodal world model of biology. By connecting insights across biological scales and modalities, Quine helps scientists computationally search a space far larger than intuition allows and prioritize hypotheses before they reach the lab. Experimental results provide important feedback, helping researchers sharpen future research directions.

Since launching a year ago, the Microsoft Research Asia — Singapore lab has established a strong foundation, deepened collaboration across government, academia, and industry, and explored how frontier AI research can create real-world value.
